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Pure Appl. Chem. 75(2-3), 231-234, 2003

Pure and Applied Chemistry

Vol. 75, Issue 2-3

Total synthesis of (�)-clavukerin A

E. L. Grimm, J.-L. Methot, and M. Shamji

Merck Frosst Centre for Therapeutic Research, P.O.Box 1005, Pointe Claire-Dorval, Québec, H9R 4P8 Canada

Abstract: (–)-Clavukerin A has been synthesized via intramolecular Julia coupling and intramolecular sulfone ester cyclization starting from (+)-limonene oxide.

*Pure Appl.Chem. 75, 141�419 (2003). An issue of reviews and research papers based on lectures presented at the 23rd IUPAC International Symposium on the Chemistry of Natural Products, Florence, Italy, 28 July � 2 August 2002.


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